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3-2a Carcinogenesis Part 1

CARCINOGENESIS I. BASIC PRINCIPLES A. Cancer formation is initiated by damage to DNA of stem cells. The damage overcomes DNA repair mechanisms, but is not lethal. i. Carcinogens are agents that damage DNA, increasing the risk for cancer. Important carcinogens include chemicals, oncogenic viruses, and radial ion (Table 3.2). B. …

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