Home / Article


Thyroid Hormone Synthesis

The first step in the synthesis of thyroid hormones is the organification of iodine.  Iodide is taken up, converted to iodine, and then condensed onto tyrosine residues which reside along the polypeptide backbone of a protein molecule called thyroglobulin.  This reaction results in either a mono-iodinated tyrosine (MIT) or di-iodinated …

Read More »

Embryology of the heart

Basic Heart Development Timeline   Embryonic Folding The disc-like embryo then undergoes a process of folding, in which both the cranial and lateral parts of the embryo fold ventrally (forwards). This brings the heart-forming region to a ventral (frontal) position. The following animation shows the development of the heart tubes …

Read More »